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- You can find more data on the above topics in some of our recent publications:
Munch-Petersen, B., J. Piskur and L. Soendergaard (1998) J. Biol. Chem. 273: 3926.
Munch-Petersen, B., W. Knecht, C. Lenz, L. Søndergaard and J. Piskur (2000) 275: 6673.
Knecht, W., B. Munch-Petersen and J. Piskur (2000) J. Mol. Biol. 301: 827.
Knecht, W., B. Munch-Petersen, and J. Piskur (2000) Polyclonal Antibodies against the
ultrafast multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster. In:
Purine and Pyrimidine Metabolism in Man X (E. Zoref-Shani and O. Sperling, Eds.),
Kluyver Academic / Plenum Press, New York.
Johansson, K., S. Ramaswamy, C. Ljungcrantz, W. Knecht, J. Piskur, B. Munch-Petersen,
S. Ericsson and H. Eklund (2001) Nature Structural Biology 8: 616.
Knecht, W, G.E. Petersen G.E.,B. Munch-Petersen and J. Piskur (2002). J. Mol. Biol. 315: 529.
Knecht, W., M.P.B. Sandrini, K. Johansson, H. Eklund, B. Munch-Petersen and J. Piskur (2002). EMBO J 21: 1873.
Knecht, W., G.E. Petersen, M.P.B. Sandrini, L. Søndergaard, B. Munch-Petersen and J. Piskur (2003) Mosquito has a single multisubstrate deoxyribonucleoside kinase characterised by unique substrate specificity. Nucleic Acids Res. 31: 1665-1672.
Mikkelsen, N.E., K. Johansson, A. Karlsson, W. Knecht, G. Andersen, J. Piskur, B. Munch-Petrsen and H. Eklund (2003) Structural basis for feedback inhibition of the Drosophila multisubstrate deoxyribonucleoside kinase. Biochemistry 42: 5706 – 5712.
Vernis, L., J. Piskur and J.F. Diffley (2003) Reconstruction of an efficient thymidine salvage pathway in Saccharomyces cerevisiae. Nucleic Acids Res. 31: (in press)
Piskur, J., Sandrini, M.P., Knecht, W. and Munch-Petersen, B. (2004) Animal deoxyribonucleoside kinases: ‘forward’ and ‘retrograde’ evolution of their substrate specificity. FEBS Lett. 560: 3-6.
Sandrini, M.P.B. and J. Piškur (2005) Deoxyribonucleoside kinases: two enzyme families catalyze the same reaction. Trends Biochem. Sci. 30: 225- 228.
Legent, K., Mas, M., Dutriaux, A., Bertrandy, S., Flagiello, D., Delanoue, R., Piskur, J. And Silber, J. (2006) In vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance. Cell Cycle 5: 740-749.
Sandrini, M.P.B., Clausen, A.R., Munch-Petersen, B. and Piskur, J. (2006) Thymidine kinase diversity in bacteria. Nucleosides, Nucleotides and Nucleic Acids 25: 1153-1158.
Clausen, A.R., Matakos, A., Sandrini, M.P.B., and Piskur, J. (2006) Thymidine kinases in archaea. Nucleosides, Nucleotides and Nucleic Acids 25: 1159-1163.
Munch-Petersen, B. and Piskur, J. (2006) Deoxynucleoside kinases and their potential role in deoxynucleoside cytotoxicity. In Deoxynucleoside analogs in cancer therapy (Peters, G.J., Ed.). Humana Press, Totowa, New Jersey.
Kosinska, U., Carnrot, C., Sandrini, M.P.B., Clausen, A.R., Wang, L., Piskur, J., Eriksson, S. and Eklund H. (2007) Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding. FEBS J 274: 727-737.
Sandrini, M.P.B., Söderbom, F., Mikkelsen, N.E., Eklund, H. And Piskur J. (2007) Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacteria-like deoxyribonulceoside kinases J. Mol. Biol. 369: 653-664.
Sandrini, M.P.B., Shannon, O., Clausen, A.R., Björck, L. and Piskur, J. (2007) Deoxyribonucleoside kinases activate nucleoside-based antibiotics in clinically important staphylococci and streptococci. Antimicrobial Agents and Chemotherapy 51: 2726-2732.
Piskur, J., Schnackerz, K.D., Andersen, G. and Björnberg, O. (2007) Comparative genomics helps to elucidate novel biochemical pathways. Trends Genet 23: 369-372.
Sandrini, M.P.B., Clausen, A.R., On, S.L.W., Aarestrup, M., Munch-Petersen, B. and Piskur, J. (2007) Nucleoside analogs are activated by bacterial deoxyribonucleoside kinases and can serve as species specific antibiotics. Journal of Antimicrobial Chemotherapy 60: 510-520.
Knecht, W., Rozpedowska, E., Le Breton, C., Willer, M., Gojkovic, Z., Sandrini, M.P.B., Joergensen, T., Hasholt, L. Munch-Petersen, B. and Piskur, J. (2007) Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs. Gene Therapy 14: 1278-1286.
Clausen, A.R., Girandon, L., Knecht, W., Survery, S., Andreasson, E., Munch-Petersen, B. and Piskur, J. (2008) A multisubstrate deoxyribonucleoside kinase from plants. Nucleic Acids Symp Ser (Oxford) 52: 489-490.
Liljas, A., Liljas, L., Kjeldgaard, M., Lindblom, G., Nissen, P., and Piskur, J. (2008) Structural Biology, a text-book. World Scientific, Singapore (in press).
Patent applications
Munch-Petersen, B., J. Piskur, L. Søndergaard and H.-G. Ihlenfeldt (1998): Deoxynukleosidkinase aus insektenzellen zur Nukleosidmonophosphat synthese. German patent application DE 198 46838.5.
Knecht, W., Munch-Petersen, B. and J. Piskur (2000): Novel nucleoside kinase enzyme variants. Danish patent application DK PA-2000 00781. PCT WO 01/88106 A2.
Knecht, W., Munch-Petersen, B. and J. Piskur (2002): Plant thymidine kinases. Danish patent application DK PA 2002 00794. PCT WO 03/100045 A1.
Knecht, W., Munch-Petersen, B. and J. Piskur: Plant deoxyribonucleoside kinases (dNK). Danish patent application DK PA 2002 00981, PCT WO 2004/003185 A2.
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