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(DEOXY)RIBONUCLEOSIDE KINASES
We can help you with detection and measurment of (deoxy)ribonucleoside
kinase activity in various biological materials, purification and isolation
of (deoxy)ribonucleoside kinases from different sources, their expression
in suitable host organisms, characterisation of their kinetic properties
and substrate specificity.
ANTI-CANCER and ANTI-VIRAL DRUGS
Among substrates of (deoxy) ribonucleoside kinases there are many analogues,
which are used as anti-cancer and anti-viral drugs, and molecular biology chemicals,
which are used in research, analysis and diagnostics. We can help you if you need
to phosphorylate any of these substrates. We can also help you to design novel
biologically active nucleoside analogues.
GENE THERAPY
(Deoxy)ribonucleoside kinases and the corresponding genes are employed in gene-
therapy, for example as suicide genes in human cell lines to be used for transplantation
purposes, or in cancer and virus-infected cells. We can help you with development of novel
suicide genes.
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